| Identification |
|---|
| HMDB Protein ID
| CDBP04942 |
| Secondary Accession Numbers
| Not Available |
| Name
| GEM-interacting protein |
| Description
| Not Available |
| Synonyms
|
- GMIP
|
| Gene Name
| GMIP |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in intracellular signaling pathway |
| Specific Function
| Stimulates, in vitro and in vivo, the GTPase activity of RhoA |
| GO Classification
|
| Component |
| cell part |
| intracellular |
| Process |
| biological regulation |
| regulation of biological process |
| regulation of cellular process |
| signal transduction |
| intracellular signaling pathway |
| signaling |
| signaling pathway |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 19p13.11 |
| SNPs
| GMIP |
| Gene Sequence
|
>2913 bp
ATGGACGCAGCAGAGCCGGGACTCCCCCCAGGTCCTGAGGGCAGGAAGAGGTACAGTGAC
ATCTTCCGGAGCCTGGACAACCTCGAAATCTCACTGGGGAACGTGACCCTTGAGATGCTG
GCTGGAGACCCTCTACTCTCAGAAGACCCAGAACCTGACAAGACCCCTACAGCCACTGTT
ACCAACGAAGCCAGCTGTTGGAGCGGCCCCTCCCCAGAGGGTCCTGTACCCCTCACAGGG
GAGGAACTGGACTTGCGGCTCATTCGGACAAAGGGGGGTGTGGACGCAGCCCTGGAATAT
GCCAAGACCTGGAGCCGCTATGCCAAGGAACTGCTTGCCTGGACTGAAAAGAGAGCCAGC
TATGAGCTGGAGTTTGCTAAGAGCACCATGAAGATCGCTGAAGCTGGCAAGGTGTCCATT
CAACAGCAGAGCCACATGCCTCTGCAGTACATCTACACCCTGTTTCTGGAGCACGATCTC
AGCCTGGGAACCCTGGCCATGGAGACAGTGGCCCAGCAGAAAAGAGACTACTACCAGCCC
CTCGCCGCCAAACGGACTGAGATTGAGAAGTGGCGGAAGGAGTTCAAGGAGCAGTGGATG
AAGGAGCAGAAGCGGATGAATGAGGCGGTGCAGGCACTGCGGCGCGCCCAGCTGCAGTAT
GTGCAACGCAGCGAGGACCTGCGGGCACGCTCCCAGGGGTCCCCTGAGGACTCGGCCCCC
CAGGCCTCGCCGGGACCTAGCAAGCAGCAGGAGCGGCGGCGGCGCTCGCGAGAGGAGGCC
CAGGCCAAGGCGCAGGAGGCCGAGGCGCTGTACCAGGCCTGTGTCCGCGAGGCCAACGCG
CGGCAGCAGGACCTGGAGATCGCCAAGCAGCGAATCGTGTCGCACGTGCGCAAGCTGGTG
TTTCAGGGGGATGAAGTGCTGAGGCGGGTGACGCTGAGTCTCTTCGGGCTGCGGGGGGCG
CAGGCAGAGCGTGGCCCCCGCGCCTTCGCCGCCCTGGCCGAGTGCTGTGCGCCCTTTGAG
CCGGGCCAGCGCTACCAGGAGTTTGTACGGGCGCTGCGGCCCGAGGCCCCGCCGCCCCCG
CCGCCCGCCTTCTCCTTCCAGGAGTTCCTTCCCTCCTTGAACAGCTCCCCTCTGGACATC
AGAAAGAAGCTCTCTGGGCCTCTTCCTCCAAGGCTGGATGAGAATTCAGCTGAGCCAGGC
CCTTGGGAGGATCCGGGCACAGGCTGGCGCTGGCAAGGGACTCCAGGCCCCACTCCGGGC
AGCGATGTGGACAGCGTGGGTGGCGGCAGCGAGTCTCGGTCCCTGGACTCACCCACTTCC
AGCCCAGGCGCTGGCACGAGGCAGCTGGTGAAGGCTTCGTCCACAGGCACTGAGTCCTCA
GATGACTTTGAGGAGCGAGACCCTGACCTGGGAGACGGGCTGGAGAATGGGCTGGGCAGC
CCCTTCGGGAAGTGGACACTGTCCAGCGCGGCTCAGACCCACCAGCTGCGGCGACTGCGG
GGCCCAGCCAAGTGCCGCGAGTGCGAAGCCTTCATGGTCAGCGGGACGGAGTGTGAGGAG
TGCTTTCTGACCTGCCACAAGCGCTGCCTGGAGACTCTCCTGATCCTCTGTGGACACAGG
CGGCTCCCAGCCCGGACACCCCTTTTTGGGGTTGACTTCCTGCAGCTACCCAGGGACTTC
CCGGAGGAGGTACCCTTTGTGGTCACGAAGTGCACGGCTGAGATAGAACACCGTGCCCTG
GATGTGCAGGGCATTTACCGGGTCAGCGGGTCCCGGGTCCGTGTGGAGCGGCTGTGCCAG
GCTTTCGAGAATGGCCGAGCGTTGGTGGAGCTGTCGGGGAACTCGCCTCATGACGTCTCG
AGTGTCCTCAAGCGATTTCTTCAGGAGCTCACCGAGCCCGTGATCCCCTTCCACCTCTAC
GACGCCTTCATCTCTCTGGCTAAGACCTTGCATGCAGACCCTGGGGACGACCCTGGGACC
CCCAGCCCCAGCCCTGATGTTATCCGCTCGCTGAAGACCCTCTTGGTACAGCTGCCTGAC
TCTAACTACAACACCCTGCGGCACCTGGTGGCCCATCTGTTCAGGGTGGCTGCACGATTT
ATGGAAAACAAGATGTCTGCCAACAACCTGGGCATTGTGTTTGGGCCGACACTGCTGCGG
CCGCCGGACGGCCCGCGGGCAGCCAGCGCCATCCCTGTCACCTGCCTGCTGGACTCTGGG
CATCAGGCCCAGCTTGTGGAGTTCCTCATCGTGCACTACGAGCAGATCTTTGGGATGGAT
GAGCTCCCCCAGGCCACTGAGCCCCCGCCCCAAGACTTCAGCCCAGCCCCTGGGCCCCTC
ACAACCAGCTCCCAACCGCCACCCCCGCACCTTGACCCAGACTCCCAGCCCCCAGTCCTA
GCCTCAGACCCCGGCCCAGACCCCCAGCACCACAGTACCCTGGAGCAGCATCCCACGGCC
ACACCTACCGAGATTCCAACTCCACAGAGTGACCAGAGAGAGGACGTGGCTGAAGACACC
AAAGATGGGGGAGGGGAAGTGTCCAGCCAAGGCCCAGAGGACTCACTCCTGGGGACACAG
TCTCGTGGCCACTTCAGCCGCCAGCCATGTAAGTATCCCCGGGGCGGTGTGAGGCCTGTA
ACCCACCAGCTGTCCAGTCTGGCCCTGGTGGCTTCCAAGCTGTGCGAGGAGACCCCCATC
ACATCAGTGCCCAGAGGGAGTTTGCGGGGGCGGGGGCCCAGCCCTGCAGCTGCCTCCCCT
GAGGGCAGCCCCCTGCGCCGCACCCCGCTGCCCAAGCATTTTGAGATTACCCAGGAGACA
GCCCGGCTACTCTCGAAATTGGACAGCGAGGCTGTGCCCAGGGCCACCTGCTGCCCGGAC
GTCCAGCCTGAGGAAGCCGAGGACCATCTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 970 |
| Molecular Weight
| 106681.8 |
| Theoretical pI
| 5.46 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>GEM-interacting protein
MDAAEPGLPPGPEGRKRYSDIFRSLDNLEISLGNVTLEMLAGDPLLSEDPEPDKTPTATV
TNEASCWSGPSPEGPVPLTGEELDLRLIRTKGGVDAALEYAKTWSRYAKELLAWTEKRAS
YELEFAKSTMKIAEAGKVSIQQQSHMPLQYIYTLFLEHDLSLGTLAMETVAQQKRDYYQP
LAAKRTEIEKWRKEFKEQWMKEQKRMNEAVQALRRAQLQYVQRSEDLRARSQGSPEDSAP
QASPGPSKQQERRRRSREEAQAKAQEAEALYQACVREANARQQDLEIAKQRIVSHVRKLV
FQGDEVLRRVTLSLFGLRGAQAERGPRAFAALAECCAPFEPGQRYQEFVRALRPEAPPPP
PPAFSFQEFLPSLNSSPLDIRKKLSGPLPPRLDENSAEPGPWEDPGTGWRWQGTPGPTPG
SDVDSVGGGSESRSLDSPTSSPGAGTRQLVKASSTGTESSDDFEERDPDLGDGLENGLGS
PFGKWTLSSAAQTHQLRRLRGPAKCRECEAFMVSGTECEECFLTCHKRCLETLLILCGHR
RLPARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQ
AFENGRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGT
PSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLR
PPDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPL
TTSSQPPPPHLDPDSQPPVLASDPGPDPQHHSTLEQHPTATPTEIPTPQSDQREDVAEDT
KDGGGEVSSQGPEDSLLGTQSRGHFSRQPVKYPRGGVRPVTHQLSSLALVASKLCEETPI
TSVPRGSLRGRGPSPAAASPEGSPLRRTPLPKHFEITQETARLLSKLDSEAVPRATCCPD
VQPEEAEDHL
|
| External Links |
|---|
| GenBank ID Protein
| 7380947 |
| UniProtKB/Swiss-Prot ID
| Q9P107 |
| UniProtKB/Swiss-Prot Entry Name
| GMIP_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF132541 |
| GeneCard ID
| GMIP |
| GenAtlas ID
| GMIP |
| HGNC ID
| HGNC:24852 |
| References |
|---|
| General References
| Not Available |