Cannabis Compound Database: Showing Protein AMP deaminase 3 (CDBP00564)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP00564

Secondary Accession Numbers

Not Available

Name

AMP deaminase 3

Description

Not Available

Synonyms

AMP deaminase isoform E
Erythrocyte AMP deaminase
SubName: Adenosine monophosphate deaminase (Isoform E), isoform CRA_b
SubName: cDNA FLJ76195, highly similar to Homo sapiens adenosine monophosphate deaminase (isoform E) (AMPD3),mRNA

Gene Name

AMPD3

Protein Type

Enzyme

Biological Properties

General Function

Involved in deaminase activity

Specific Function

AMP deaminase plays a critical role in energy metabolism.

GO Classification

Biological Process
purine nucleobase metabolic process
AMP catabolic process
purine-containing compound salvage
IMP salvage
Cellular Component
cytosol
Function
catalytic activity
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
amp deaminase activity
deaminase activity
Molecular Function
metal ion binding
AMP deaminase activity
Process
nitrogen compound metabolic process
cellular nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleobase, nucleoside and nucleotide metabolic process
nucleoside phosphate metabolic process
nucleotide metabolic process
cellular aromatic compound metabolic process
purine nucleoside monophosphate biosynthetic process
purine ribonucleoside monophosphate biosynthetic process
purine base metabolic process
cellular metabolic process
nucleobase metabolic process
purine nucleotide metabolic process
purine nucleotide biosynthetic process
metabolic process

Cellular Location

Cytoplasmic

Pathways

Name	SMPDB/Pathwhiz	KEGG
IMP biosynthesis via salvage pathway	Not Available	Not Available

Gene Properties

Chromosome Location

Locus

11p15

SNPs

AMPD3

Gene Sequence

>2304 bp
ATGCCGCGGCAGTTTCCCAAGCTGAACATCTCTGAAGTGGATGAGCAAGTCCGGCTCCTG
GCGGAGAAGGTGTTTGCTAAAGTGCTCCGAGAAGAGGACAGCAAAGATGCCCTGTCCCTG
TTCACTGTCCCAGAGGACTGCCCCATCGGGCAAAAGGAAGCCAAGGAGAGGGAGCTGCAG
AAGGAGCTGGCAGAGCAGAAGTCTGTGGAGACCGCAAAAAGAAAGAAAAGTTTCAAGATG
ATTCGGTCCCAGTCCCTGTCTCTGCAAATGCCGCCACAGCAAGATTGGAAGGGCCCCCCG
GCAGCCAGTCCGGCCATGTCTCCCACAACCCCTGTGGTCACTGGAGCCACTTCCCTGCCC
ACGCCAGCACCCTATGCCATGCCTGAGTTCCAGCGGGTCACCATCAGCGGAGATTACTGT
GCCGGGATCACTTTGGAGGACTATGAGCAGGCAGCCAAGAGTCTGGCCAAGGCCCTAATG
ATCCGGGAGAAGTATGCGCGGCTCGCCTACCACCGCTTCCCGCGGATCACATCCCAGTAC
CTGGGTCATCCGCGGGCGGATACTGCACCTCCGGAAGAGGGCCTTCCAGACTTCCACCCT
CCTCCACTGCCCCAGGAAGACCCCTACTGCCTGGATGATGCACCCCCCAACCTGGATTAC
TTGGTCCACATGCAGGGGGGCATCCTCTTTGTGTATGATAACAAGAAGATGCTGGAGCAC
CAGGAGCCGCACAGCCTACCCTACCCCGACCTGGAGACCTACACGGTGGACATGAGCCAC
ATCCTGGCTCTCATCACCGATGGCCCCACGAAAACCTATTGTCACCGGCGACTGAACTTT
CTGGAATCCAAGTTCAGCCTTCATGAGATGTTAAACGAAATGTCCGAGTTCAAAGAGTTG
AAGAGTAACCCCCACCGGGACTTCTATAACGTGAGAAAGGTGGACACACACATCCATGCG
GCCGCCTGCATGAACCAAAAGCATCTGCTGCGCTTCATCAAGCACACATACCAGACGGAG
CCTGACAGGACTGTGGCAGAGAAGCGGGGCCGGAAGATCACCCTGCGGCAGGTGTTTGAC
GGCCTGCACATGGACCCCTACGACCTCACTGTGGACTCACTGGATGTCCACGCGGGCCGG
CAGACATTCCACCGCTTTGACAAGTTCAACTCCAAATACAACCCTGTGGGGGCCAGTGAG
CTGCGTGACCTGTATTTGAAAACTGAAAACTATCTGGGAGGAGAGTACTTTGCTCGGATG
GTCAAGGAGGTTGCCCGGGAGCTGGAGGAGAGCAAGTACCAGTACTCAGAGCCACGGCTC
TCCATCTACGGCCGCAGTCCTGAGGAGTGGCCCAACCTGGCCTACTGGTTCATCCAGCAC
AAGGTCTACTCTCCCAACATGCGCTGGATCATCCAGGTGCCCCGGATTTATGACATATTT
AGGTCAAAGAAGCTGCTGCCAAACTTTGGGAAGATGCTGGAGAACATCTTCCTGCCCCTT
TTCAAGGCCACTATCAACCCCCAAGATCATCGAGAGCTTCACCTCTTCCTTAAATATGTG
ACGGGGTTTGACAGCGTGGATGATGAGTCCAAGCACAGCGACCACATGTTTTCCGACAAG
AGCCCAAACCCGGACGTCTGGACCAGTGAGCAGAACCCACCCTACAGCTACTACCTGTAC
TACATGTATGCCAACATCATGGTGCTCAACAACCTCCGCAGGGAGCGCGGCCTGAGCACG
TTCCTGTTCCGGCCGCACTGTGGGGAAGCCGGCTCCATCACCCACCTGGTGTCTGCCTTC
CTCACTGCTGACAACATTTCCCACGGGCTGCTCCTCAAGAAGAGTCCGGTATTGCAGTAT
CTCTACTACCTTGCTCAGATCCCCATTGCCATGTCTCCTCTTAGCAACAACAGTTTGTTC
CTCGAATATTCCAAGAACCCTCTGAGGGAATTCCTACACAAGGGACTGCATGTTTCTCTT
TCCACCGATGACCCCATGCAGTTCCACTACACGAAGGAAGCACTTATGGAAGAATATGCC
ATTGCAGCTCAAGTGTGGAAGCTGAGCACCTGCGACCTGTGTGAGATCGCCAGGAACAGC
GTGCTGCAGAGCGGCCTCTCGCATCAGGAAAAGCAAAAGTTTCTGGGACAAAATTATTAT
AAAGAAGGACCTGAAGGAAATGATATTCGAAAGACAAATGTGGCTCAGATCCGGATGGCA
TTCCGATATGAGACCTTATGCAATGAGCTCAGCTTCCTGTCTGATGCTATGAAATCAGAA
GAGATCACCGCCTTGACCAACTAG

Protein Properties

Number of Residues

767

Molecular Weight

89727.485

Theoretical pI

6.849

Pfam Domain Function

A_deaminase (PF00962 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>AMP deaminase 3
MPRQFPKLNISEVDEQVRLLAEKVFAKVLREEDSKDALSLFTVPEDCPIGQKEAKERELQ
KELAEQKSVETAKRKKSFKMIRSQSLSLQMPPQQDWKGPPAASPAMSPTTPVVTGATSLP
TPAPYAMPEFQRVTISGDYCAGITLEDYEQAAKSLAKALMIREKYARLAYHRFPRITSQY
LGHPRADTAPPEEGLPDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGILFVYDNKKMLEH
QEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKEL
KSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFD
GLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARM
VKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIF
RSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDK
SPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAF
LTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSL
STDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYY
KEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTN

External Links

GenBank ID Protein

158261019

UniProtKB/Swiss-Prot ID

Q01432

UniProtKB/Swiss-Prot Entry Name

AMPD3_HUMAN

PDB IDs

Not Available

GenBank Gene ID

D12775

GeneCard ID